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APG-1252 combined with Cabozantinib inhibits hepatocellular carcinoma through MEK/ERK and CREB/Bcl-xl pathways

2024-04-08

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<title>Abstract</title> <p>Background and Purpose Liver cancer is the fourth leading cause of cancer-related death worldwide, and hepatocellular carcinoma (HCC) is the most common primary liver cancer. APG-1252 is a small molecule inhibitor of Bcl-2/Bcl-xl, and the anti-tumor effect of APG-1252 in HCC, or its anti-tumor effects in combination with cabozantinib, has not been researched. Experimental Approach: TC...

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Literature Corpus work
68858b5a-1926-5f17-81bd-7a0f928659f2
DOI
10.21203/rs.3.rs-4206490/v1
Open publication

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APG-1252 combined with Cabozantinib inhibits hepatocellular carcinoma through MEK/ERK and CREB/Bcl-xl pathwaysDOI 10.21203/rs.3.rs-4206490/v1
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