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Kaempferol induces DNA damage, cell apoptosis and cell cycle arresting by promoting DNA-PKcs ubiquitination degradation in Bel-7402/5-Fu cells

2023-04-11

Abstract excerpt

<h4>Purpose: </h4> Drug resistance is the main cause of chemotherapy failure in hepatocellular carcinoma. Kaempferol (KAE) is a natural flavonoid compound, which has a certain chemo-sensitivity enhancement effect. However, the potential molecular mechanism of KAE reversing drug resistance in hepatocellular carcinoma remains unclear. <h4>Methods: </h4>: RT-qPCR was used to evaluate the interference effect of siDNA...

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Literature Corpus work
80ef7315-4412-5378-aaaa-864188321be1
DOI
10.21203/rs.3.rs-2789202/v1
Open publication

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Kaempferol induces DNA damage, cell apoptosis and cell cycle arresting by promoting DNA-PKcs ubiquitination degradation in Bel-7402/5-Fu cellsDOI 10.21203/rs.3.rs-2789202/v1
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