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Article

Discovery of Canine Drug Toceranib Phosphate as a Repurposed Agent against Human Hepatocellular Carcinoma

2022-01-31

Abstract excerpt

<h4>Background: </h4> Human hepatocellular carcinoma (HCC) is an aggressive malignancy worldwide with a poor clinical outcome. There are limited therapeutic options currently available for those diagnosed with terminal HCC and therefore incorporating novel agents into standard-of-care regimens is urgently needed. In contrast to de novo drug discovery, the strategy of repurposing already-approved compounds initiall...

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Literature Corpus work
245ac3df-7367-5aa8-9984-762b3c3ce638
DOI
10.21203/rs.3.rs-1298194/v1
Open publication

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