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Article

Transcriptomic-Assisted Immune and Neoantigen Profiling in Premalignancy.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022

Chang Kyle, McAllister Florencia, Vilar Eduardo

Abstract excerpt

Immune-based cancer therapies such as checkpoint inhibitors (CPI) and vaccines have been increasingly studied across different cancer types. Response to such therapies depends on a number of factors such as mutational burden, neoantigen load, presence of tumor infiltrating lymphocytes, among others. Next-generation sequencing (NGS) technologies are particularly attractive to interrogate the immune response...

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Identifiers

PMID: 34993941
DOI: 10.1007/978-1-0716-2014-4_7
PMCID: PMC11073470

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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