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Toxicity of microplastics and plastic additive co-exposure in liver Disse organoids from healthy donors and patient-derived induced pluripotent stem cells

2022-09-15

Abstract excerpt

The ubiquitous microplastics (MPs) and plastic additives in the environment usually form complexes, enter human blood circulation, and increase the risk of steatohepatitis. The liver Disse space plays a vital role in corresponding hepatic pathological processes. However, due to the limited understanding of the regulatory cues in multilineage maturation, the generation of large-scale Disse-like organoids (DOs) mirr...

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Literature Corpus work
fc0c5b4e-fe5a-56c1-82a3-0f7c269c60ca
DOI
10.1101/2022.09.12.506301
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Toxicity of microplastics and plastic additive co-exposure in liver Disse organoids from healthy donors and patient-derived induced pluripotent stem cellsDOI 10.1101/2022.09.12.506301
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