Article

Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays

2024-03-29

Abstract excerpt

Human liver organoids (HLOs) differentiated from embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and adult stem cells (ASCs) can recapitulate the structure and function of human fetal liver tissues, thus being considered as a promising tissue model for liver diseases and predictive compound screening. However, the adoption of HLOs in drug discovery faces several technical challenges, which inc...

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Literature Corpus work: f91498a9-979b-5656-b84b-f9a5335cb312
DOI: 10.1101/2024.03.25.586638

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