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Article

The PqsE active site as a target for small molecule antimicrobial agents against <i>Pseudomonas aeruginosa</i>

2022-04-21

Abstract excerpt

The opportunistic pathogen Pseudomonas aeruginosa causes antibiotic resistant, nosocomial infections in immuno-compromised individuals, and is a high priority for antimicrobial development. Key to pathogenicity in P. aeruginosa are biofilm formation and virulence factor production. Both traits are controlled by the cell-to-cell communication process called quorum sensing (QS). QS involves the synthesis, release,...

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Literature Corpus work
fbc6e575-d2e2-514a-b1a7-33cabdd6497b
DOI
10.1101/2022.04.21.489002
Open publication

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The PqsE active site as a target for small molecule antimicrobial agents against <i>Pseudomonas aeruginosa</i>DOI 10.1101/2022.04.21.489002
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