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Screening of FDA-approved small molecules to discover inhibitors of the <i>Pseudomonas aeruginosa</i> quorum-sensing enzyme, PqsE

2025-07-25

Abstract excerpt

Pseudomonas aeruginosa is a notorious pathogen that is a leading cause of hospital-acquired infections. Due to its heightened resistance to a broad range of antibiotics, there is great need for new antimicrobial agents that are effective in treating P. aeruginosa infections. One attractive option for exploring new antibiotic targets is the quorum sensing (QS) pathway, as it governs many of the pathogenic behavior...

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Literature Corpus work
067eac86-d34e-5b8d-9576-8efd78785230
DOI
10.1101/2025.07.25.666791
Open publication

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