Resistance of SARS-CoV-2 variants to neutralization by antibodies induced in convalescent patients with COVID-19.

doi:10.1016/j.celrep.2021.109385

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Resistance of SARS-CoV-2 variants to neutralization by antibodies induced in convalescent patients with COVID-19.

Cell reports - 13 Jul 2021

Kaku Yu, Kuwata Takeo, Zahid Hasan Md, Hashiguchi Takao, Noda Takeshi, Kuramoto Noriko, Biswas Shashwata, Matsumoto Kaho, Shimizu Mikiko, Kawanami Yoko, Shimura Kazuya, Onishi Chiho, Muramoto Yukiko, Suzuki Tateki, Sasaki Jiei, Nagasaki Yoji, Minami Rumi, Motozono Chihiro, Toyoda Mako, Takahashi Hiroshi, Kishi Hiroto, Fujii Kazuhiko, Tatsuke Tsuneyuki, Ikeda Terumasa, Maeda Yosuke, Ueno Takamasa, Koyanagi Yoshio, Iwagoe Hajime, Matsushita Shuzo

Abstract excerpt

Administration of convalescent plasma or neutralizing monoclonal antibodies (mAbs) is a potent therapeutic option for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, SARS-CoV-2 variants with mutations in the spike protein have emerged in many countries. To evaluate the efficacy of neutralizing antibodies induced in convalescent...

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Identifiers

PMID: 34237284
DOI: 10.1016/j.celrep.2021.109385
PMCID: PMC8226103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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