Article

A Protocol for Revealing Oral Neutrophil Heterogeneity by Single-Cell Immune Profiling in Human Saliva

2020-07-02

Abstract excerpt

<title>Abstract</title> <p>Neutrophils are the most abundant white blood cells in the human body responsible for fighting viral, bacterial and fungi infections. Out of the 100 billion neutrophils produced daily, it is estimated that 10 % of these cells end up in oral biofluids. Because saliva is a fluid accessible through non-invasive techniques, it is an optimal source of cells and molecule surveillance in healt...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fb861b69-1fac-5902-94ad-b39efd9bd4a0
DOI: 10.21203/rs.3.pex-953/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Protocol for Revealing Oral Neutrophil Heterogeneity by Single-Cell Immune Profiling in Human SalivaDOI 10.21203/rs.3.pex-953/v2Read

Comparison of Fixed Single Cell RNA-seq Methods to Enable Transcriptome Profiling of Neutrophils in Clinical SamplesSemantic proximity Read

Single cell sequencing of neutrophils demonstrates phenotypic heterogeneity and functional plasticity in health, disease, and cancer.Semantic proximity Read

Single-cell analysis reveals the range of transcriptional states of circulating human neutrophilsSemantic proximity Read

Decoding circulating neutrophil phenotypes in triple-negative breast cancer via optimized single-cell RNA sequencing.Semantic proximity Read

Multi-Omics Profiling Reveals Phenotypic and Functional Heterogeneity of Neutrophils in COVID-19.Semantic proximity Read

Oral neutrophils display a site-specific phenotype characterized by expression of T-cell receptors.Semantic proximity Read

Single-cell atlas of human oral mucosa reveals a stromal-neutrophil axis regulating tissue immunity in health and inflammatory diseaseSemantic proximity Read

Single-cell transcriptome profiling reveals neutrophil heterogeneity and orchestrated maturation during homeostasis and bacterial infectionSemantic proximity Read

Multi-omics profiling reveals phenotypic and functional heterogeneity of neutrophils in COVID-19Semantic proximity Read

Epigenomic and functional dynamics of human bone marrow myeloid differentiation to mature blood neutrophilsSemantic proximity Read

Heterogeneity of neutrophils and inflammatory responses in patients with COVID-19 and healthy controlsSemantic proximity Read

Salivary Neutrophil Sampling Feasibility in General Population for Gene Expression AnalysisSemantic proximity Read