Article

GLnexus: joint variant calling for large cohort sequencing

2018-06-11

Abstract excerpt

<h4>ABSTRACT</h4> As ever-larger cohorts of human genomes are collected in pursuit of genotype/phenotype associations, sequencing informatics must scale up to yield complete and accurate genotypes from vast raw datasets. Joint variant calling, a data processing step entailing simultaneous analysis of all participants sequenced, exhibits this scaling challenge acutely. We present GLnexus (GL, Genotype Likelihood)...

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Literature Corpus work: fb1480cc-b25b-5066-b8d7-7fcd9679b103
DOI: 10.1101/343970

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