Article
Inexpensive and Highly Reproducible Cloud-Based Variant Calling of 2,535 Human Genomes.
PloS one - 1 Jan 2015
Shringarpure Suyash S, Carroll Andrew, De La Vega Francisco M, Bustamante Carlos D
Abstract excerpt
Population scale sequencing of whole human genomes is becoming economically feasible; however, data management and analysis remains a formidable challenge for many research groups. Large sequencing studies, like the 1000 Genomes Project, have improved our understanding of human demography and the effect of rare genetic variation in disease. Variant calling on datasets of hundreds or thousands of genomes is...
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