Back to search

Article

Genotype Representation Graphs: Enabling Efficient Analysis of Biobank-Scale Data

2024-04-28

Abstract excerpt

Computational analysis of a large number of genomes requires a data structure that can represent the dataset compactly while also enabling efficient operations on variants and samples. Current practice is to store large-scale genetic polymorphism data using tabular data structures and file formats, where rows and columns represent samples and genetic variants. However, encoding genetic data in such formats has bec...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
35bddfe2-6f74-5d04-bcd8-6f197993e10a
DOI
10.1101/2024.04.23.590800
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genotype Representation Graphs: Enabling Efficient Analysis of Biobank-Scale DataDOI 10.1101/2024.04.23.590800
Enabling efficient analysis of biobank-scale data with genotype representation graphs.Semantic proximity
Graphtyper: Population-scale genotyping using pangenome graphsSemantic proximity
Fast and Accurate Genomic Analyses using Genome GraphsSemantic proximity
The Great Genotyper: A Graph-Based Method for Population Genotyping of Small and Structural VariantsSemantic proximity
Graphtyper enables population-scale genotyping using pangenome graphs.Semantic proximity
The Great Genotyper: a graph-based method for population genotyping of small and structural variants.Semantic proximity
GViNC: an innovative framework for genome graph comparison reveals hidden patterns in the genetic diversity of human populationsSemantic proximity
KAGE: fast alignment-free graph-based genotyping of SNPs and short indels.Semantic proximity
Efficient genotype compression and analysis of large genetic variation datasetsSemantic proximity
StrPhaser constructs tandem repeat alleles from VCF dataSemantic proximity
Population-specific genome graphs improve high-throughput sequencing data analysis: A case study on the Pan-African genomeSemantic proximity
Genome Graphs and the Evolution of Genome InferenceSemantic proximity
Select a neighboring publication to make it the new centre.