Article

Efficient genotype compression and analysis of large genetic variation datasets

2015-04-20

Abstract excerpt

<h4>ABSTRACT</h4> The economy of human genome sequencing has catalyzed ambitious efforts to interrogate the genomes of large cohorts in search of new insight into the genetic basis of disease. This manuscript introduces Genotype Query Tools (GQT) as a new indexing strategy and toolset that addresses an analytical bottleneck by enabling interactive analyses based on genotypes, phenotypes and sample relationships....

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Literature Corpus work: 2e262139-d2e9-58fd-9b98-9518592302a4
DOI: 10.1101/018259

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