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Genotype and dose-frequency determine acute and chronic effects of oxytocin on amygdala fear responses in humans: therapeutic implications

2018-12-11

Abstract excerpt

<h4>Background</h4> There is considerable interest in therapeutic application of intranasal oxytocin in psychiatric disorders, but while clinical trials typically use daily dosing protocols it has not been established whether this is optimal or if there are moderating influences of oxytocin receptor genotype. <h4>Methods</h4> In a randomized, placebo-controlled pre-registered trial on 138 adult male subjects we...

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Literature Corpus work
fb0c2194-fc32-5f84-8e38-337d24c37cd3
DOI
10.1101/493387
Open publication

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Genotype and dose-frequency determine acute and chronic effects of oxytocin on amygdala fear responses in humans: therapeutic implicationsDOI 10.1101/493387
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