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Article

A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocin.

Psychological medicine - 1 Jul 2022

Kou Juan, Zhang Yingying, Zhou Feng, Sindermann Cornelia, Montag Christian, Becker Benjamin, Kendrick Keith M

Abstract excerpt

BACKGROUND: The neuropeptide oxytocin is proposed as a promising therapy for social dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical trials report some benefits of chronic treatment, it is unclear whether efficacy may be influenced by dose frequency or genotype. METHODS: In a randomized, double-blind, placebo-controlled pharmaco-functional magnetic resonance imaging trial...

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Identifiers

PMID: 33272333
DOI: 10.1017/S0033291720003803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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