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A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocin

2020-08-25

Abstract excerpt

<h4>Background</h4> The neuropeptide oxytocin is proposed as a promising therapy for social dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical trials report some benefits of chronic treatment it is unclear whether efficacy may be influenced by dose frequency or genotype. <h4>Methods</h4> In a randomized, double blind, placebo-controlled pharmaco-fMRI trial (150 male subjects)...

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Literature Corpus work
6ae8226d-647b-56f7-a995-a1188edbfa2a
DOI
10.1101/2020.08.23.20180489
Open publication

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A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocinDOI 10.1101/2020.08.23.20180489
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