Article

Genetic and epigenetic signatures associated with plasma oxytocin levels in children and adolescents with autism spectrum disorder

2022-05-30

Abstract excerpt

<h4>ABSTRACT</h4> Oxytocin (OT), the brain’s most abundant neuropeptide, plays an important role in social salience and motivation. Clinical trials of the efficacy of OT in autism spectrum disorder (ASD) have reported mixed results due in part to ASD’s complex etiology. We hypothesized that genetic and epigenetic variation contribute to variable endogenous OT levels that modulate sensitivity to OT therapy. To test...

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Literature Corpus work: f0af6abc-8247-5cf1-ab7c-378c6779b4f3
DOI: 10.1101/2022.05.26.22275542

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