Article

The natural product erianin induces melanoma apoptosis through targeting the GSK3α-NF-κB pathway

2022-11-15

Abstract excerpt

Erianin has been reported to play key roles in suppressing a wide variety of tumors. However, the anti-carcinogenic mechanism underlying erianin remains to be fully elucidated. The half-maximal inhibitory concentration (IC 50 ) was assessed to determine the influence of erianin on melanoma in vitro. In vivo , tumor-bearing models in nude mice were established to investigate the impact of erianin on the growth of m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fb003ecb-aefa-5b27-a74d-8b81c41c5554
DOI: 10.21203/rs.3.rs-2235822/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The natural product erianin induces melanoma apoptosis through targeting the GSK3α-NF-κB pathwayDOI 10.21203/rs.3.rs-2235822/v1Read

Anticancer Activity of Euplotin C, Isolated from the Marine Ciliate Euplotes crassus, Against Human Melanoma CellsSemantic proximity Read

Phytochemicals for the Management of Melanoma.Semantic proximity Read

In vivo antitumoral effect of 4-nerolidylcatechol (4-NC) in NRAS-mutant human melanoma.Semantic proximity Read

β,β-Dimethylacrylshikonin Induces Apoptosis in Melanoma Cell Lines by NOXA Upregulation.Semantic proximity Read

Exploring Medicinal Mechanism of Baicalin in Tumor Microenvironment of Melanoma via Bioinformatic and In Vitro StudySemantic proximity Read

Investigation of the mechanism of the anti-cancer effects of Astragalus propinquus Schischkin and Pinellia pedatisecta Schott (A&P) on melanoma via network pharmacology and experimental verificationSemantic proximity Read

The Ashitaba (Angelica keiskei) Chalcones 4-hydroxyderricin and Xanthoangelol Suppress Melanomagenesis By Targeting BRAF and PI3K.Semantic proximity Read

Gossypin as a novel selective dual inhibitor of V-RAF murine sarcoma viral oncogene homolog B1 and cyclin-dependent kinase 4 for melanoma.Semantic proximity Read

Bufalin-Mediated Regulation of Cell Signaling Pathways in Different Cancers: Spotlight on JAK/STAT, Wnt/β-Catenin, mTOR, TRAIL/TRAIL-R, and Non-Coding RNAsSemantic proximity Read

Evidence of<i>γ</i>-Tocotrienol as an Apoptosis-Inducing, Invasion-Suppressing, and Chemotherapy Drug-Sensitizing Agent in Human Melanoma CellsSemantic proximity Read

Anticancer Activity of Erianin: Cancer-Specific Target Prediction Based on Network PharmacologySemantic proximity Read

Natural products targeting the MAPK-signaling pathway in cancer: overviewSemantic proximity Read