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Article

A functional genomic meta-analysis of clinical trials in systemic sclerosis: towards precision medicine and combination therapy

2016-11-13

Abstract excerpt

<h4>ABSTRACT</h4> Systemic sclerosis (SSc) is an orphan, systemic autoimmune disease with no FDA-approved treatments. Its heterogeneity and rarity often result in underpowered clinical trials making the analysis and interpretation of associated molecular data challenging. We performed a meta-analysis of gene expression data from skin biopsies of SSc patients treated with five therapies: mycophenolate mofetil (MMF...

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Literature Corpus work
fabc2c9b-64a9-542e-8c1d-850307bee41c
DOI
10.1101/087361
Open publication

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A functional genomic meta-analysis of clinical trials in systemic sclerosis: towards precision medicine and combination therapyDOI 10.1101/087361
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