Article

Reduced β2-glycoproteinI Alleviated Rat Myocardial Ischemia/Reperfusion Injury via Mitochondrial Protection and Inhibition of Apoptosis

2020-10-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Myocardial ischemia/reperfusion (I/R) injury is one of the most important reasons for death of coronary heart disease after vascular recanalization. New evidences have shown that β2-glycoprotein I (β2GPI) plays a protective role in cardiovascular diseases. This study aims to evaluate the effects of reduced β2GPI (R-β2GPI), one form of β2GPI, on myocardial I/R inju...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fa9fb9c7-541d-5534-983e-8ad1b43d474f
DOI: 10.21203/rs.3.rs-87087/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Reduced β2-glycoproteinI Alleviated Rat Myocardial Ischemia/Reperfusion Injury via Mitochondrial Protection and Inhibition of ApoptosisDOI 10.21203/rs.3.rs-87087/v1Read

The Shexiang Baoxin Pill Protects Myocardial Cells from Multiple Targets of MIRI through the PI3K/Akt/eNOS Signal PathwaySemantic proximity Read

MicroRNA-214 protects against hypoxia/reoxygenation induced cell damage and myocardial ischemia/reperfusion injury via suppression of PTEN and Bim1 expressionSemantic proximity Read

miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosisSemantic proximity Read

Ischemia/Reperfusion Injury: Pathophysiology, Current Clinical Management, and Potential Preventive Approaches.Semantic proximity Read

Dexmedetomidine attenuates the injury of H9C2 cardiomyocytes under Hypoxia/reoxygenation condition partly through the inhibition of endoplasmic reticulum stressSemantic proximity Read

Bioinformatic Analysis of the Protective Effects of Dexmedetomidine and Thrombopoietin against Hypoxia/Reoxygenation-Induced Injury in AC16 CellsSemantic proximity Read

LncRNA-AK138945 Regulates Myocardial Ischemia-Reperfusion Injury Via the miR-1-GRP94 Signaling PathwaySemantic proximity Read

β-arrestin 2 mediates cardiac ischemia-reperfusion injury via inhibiting GPCR-independent cell survival signalling.Semantic proximity Read

miRNA-541-5p regulates myocardial ischemia-reperfusion injury by targeting ferroptosisSemantic proximity Read

p38 alpha mitogen-activated protein kinase inhibition improves cardiac function and reduces myocardial damage in isoproterenol-induced acute myocardial injury in rats.Semantic proximity Read

Human Urinary Kallidinogenase (HUK) Alleviates Myocardial Injury in Rats with Coronary Microembolism Through PI3K/Akt/FoxO1 Signaling Pathway.Semantic proximity Read

miR-187 Modulates Cardiomyocyte Apoptosis and Oxidative Stress in Myocardial Infarction Mice via Negatively Regulating DYRK2Semantic proximity Read