Article
LncRNA-AK138945 Regulates Myocardial Ischemia-Reperfusion Injury Via the miR-1-GRP94 Signaling Pathway
2021-09-22
Abstract excerpt
<title>Abstract</title> <p>Myocardial ischemia-reperfusion injury (MIRI) is one of the main causes of high mortality of cardiovascular diseases (CVD). Long non-coding RNAs (lncRNAs), as a new type of gene expression regulators, play a key role in multiple processes of CVD. In this study, myocardial apoptosis was found to be increased in both MIRI heart and hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) treated my...
Topics
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- Cancer-related molecular mechanisms research
- Chemotherapy-induced cardiotoxicity and mitigation
- Ferroptosis and cancer prognosis
- Neuroinflammation and Neurodegeneration Mechanisms
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Nitric Oxide and Endothelin Effects
- Redox biology and oxidative stress
- RNA modifications and cancer
Identifiers and source
- Literature Corpus work
- f555f85e-3ec2-5a86-bcdb-940ce6e50e96
- DOI
- 10.21203/rs.3.rs-896045/v1
