Article
Perсhlozone Resistance in Clinical Isolates of Mycobacterium tuberculosis
2023-01-17
Abstract excerpt
The emergence of drug-resistant tuberculosis forced the development of new drugs and screnning of more effective or less toxic analogs. Mycolic acids biosynthesis is targeted by several antituberculosis drugs toped by the isoniazid being one of the most important in tuberculosis therapy. Recently, perchlozone, acting on another step in FAS-II cycle, received official approval and was included in the Russian nation...
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Identifiers and source
- Literature Corpus work
- fa99ddbf-dbf9-5204-8ea4-52b88001eccc
- DOI
- 10.20944/preprints202301.0288.v1
