Article
An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition.
Infection and immunity - 1 May 2014
Ang Michelle Lay Teng, Zainul Rahim Siti Zarina, Siti Zarina Zainul Rahim, Shui Guanghou, Dianiškova Petronela, Madacki Jan, Lin Wenwei, Koh Vanessa Hui Qi, Martinez Gomez Julia Maria, Sudarkodi Sukumar, Bendt Anne, Wenk Markus, Mikušová Katarína, Korduláková Jana, Pethe Kevin, Alonso Sylvie
Abstract excerpt
Tuberculosis remains a major worldwide epidemic because of its sole etiological agent, Mycobacterium tuberculosis. Ethionamide (ETH) is one of the major antitubercular drugs used to treat infections with multidrug-resistant M. tuberculosis strains. ETH is a prodrug that requires activation within...
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