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Perturbations in mitochondrial metabolism associated with defective cardiolipin biosynthesis: An <i>in-organello</i> real-time NMR study

2024-06-22

Abstract excerpt

Mitochondria are central to cellular metabolism; hence, their dysfunction contributes to a wide array of human diseases including cancer, cardiopathy, neurodegeneration, and heritable pathologies such as Barth syndrome. Cardiolipin, the signature phospholipid of the mitochondrion promotes proper cristae morphology, bioenergetic functions, and directly affects metabolic reactions carried out in mitochondrial membra...

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Literature Corpus work
fa7d5ea8-39f5-5c6d-a939-b3b2b472c64d
DOI
10.1101/2024.06.18.599628
Open publication

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Perturbations in mitochondrial metabolism associated with defective cardiolipin biosynthesis: An <i>in-organello</i> real-time NMR studyDOI 10.1101/2024.06.18.599628
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