Article

Tandem repeat expansions in <i>DAPK1</i> , <i>ANK3</i> , and <i>RPL14</i> are associated with diverse neurodegenerative diseases

2026-08-10

Abstract excerpt

Tandem repeat expansions (TREs) cause over 50 neurological conditions, yet their contribution to neurodegenerative disease risk at a population scale remains incompletely characterized. We performed a TRE association study across 6,539 short tandem repeat loci in 276,411 individuals from the UK Biobank and 44,370 individuals from the All of Us Research Program, using two composite neurodegenerative phenotypes to i...

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Literature Corpus work: fa70c040-8705-5958-9eac-b237ef230e3d
DOI: 10.64898/2026.08.06.26358503

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