Article

Type-2-immune history imprints local training in nerve-airway associated interstitial macrophages (NAMs) for disease tolerance during respiratory viral infection

2026-02-12

Abstract excerpt

<title>Abstract</title> <p> Severe respiratory viral disease varies widely among individuals and often reflects immunopathology rather than inadequate pathogen control, suggesting that prior immune history can prime the lung’s inflammatory–regulatory balance to promote disease tolerance. Here we show that nerve- and airway-associated macrophages (NAMs), a subset of interstitial macrophages expand following type...

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Literature Corpus work: fa6f41fd-cb96-50db-9c32-82ab9b1d28bb
DOI: 10.21203/rs.3.rs-8780633/v1

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Type-2-immune history imprints local training in nerve-airway associated interstitial macrophages (NAMs) for disease tolerance during respiratory viral infectionDOI 10.21203/rs.3.rs-8780633/v1Read

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