Article

Aldehyde metabolic reprogramming in oesophageal adenocarcinoma

2017-01-01

Abstract excerpt

Oesophageal adenocarcinoma (OAC) has unmet clinical needs as the UK five-year survival is 14%. Efforts to enhance early diagnosis uncovered enriched volatile aldehydes in OAC patients' breath, although their origins and fate are unknown. Following comprehensive bioinformatics analyses, it was hypothesised that detoxification loss enriches aldehydes in the transforming lower oesophagus. Pursuing this biology could...

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Literature Corpus work: fa3a128d-967f-54e5-ae2e-fe98b74257ee
DOI: 10.25560/68288

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