Article

Epstein-Barr virus induced 3 attributes to TLR7-mediated splenomegaly and bicytopenia

2024-06-11

Abstract excerpt

Epstein-Barr virus induced 3 (EBI3) is a gene induced by stimulation of toll-like receptors (TLRs) and functions as a component of a heterodimer cytokine IL-27. IL-27 regulates both innate and acquired immune responses; however, their function in vivo is still largely unknown. Splenomegaly, an enlargement of the spleen, is known to be induced by chronic infectious diseases, including infectious mononucleosis due...

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Literature Corpus work: fa32af67-38a8-5cff-8a05-9d087a0c9b00
DOI: 10.1101/2024.06.10.598101

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