Article

Accurate and Reproducible Functional Maps in 127 Human Cell Types via 2D Genome Segmentation

2017-03-20

Abstract excerpt

<h4>ABSTRACT</h4> The Roadmap Epigenomics consortium has published whole-genome functional annotation maps in 127 human cell types and cancer cell lines by integrating data from multiple epigenetic marks. These maps have thereby been widely used by the community for studying gene regulation in cell type specific contexts and predicting functional impacts of DNA mutations on disease. Here, we present a new map of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fa101466-f252-5867-9521-6f5833421df8
DOI: 10.1101/118752

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Accurate and Reproducible Functional Maps in 127 Human Cell Types via 2D Genome SegmentationDOI 10.1101/118752Read

A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types.Semantic proximity Read

A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell typesSemantic proximity Read

Direct prediction of regulatory elements from partial data without imputationSemantic proximity Read

Jointly characterizing epigenetic dynamics across multiple human cell types.Semantic proximity Read

Pan-cell type continuous chromatin state annotation of all epigenomes from the International Human Epigenome ConsortiumSemantic proximity Read

Integrative analysis of 111 reference human epigenomes.Semantic proximity Read

Direct prediction of regulatory elements from partial data without imputation.Semantic proximity Read

Multi-scale annotations of chromatin states in 127 human cell-typesSemantic proximity Read

Integrative epigenomic and functional characterization assay based annotation of regulatory activity across diverse human cell typesSemantic proximity Read

Bayesian Modeling of Epigenetic Variation in Multiple Human Cell TypesSemantic proximity Read

Expanding TheCellMap.org to visualize a genome-scale genetic interaction network for a human cell lineSemantic proximity Read

Integrative chromatin state annotation of 234 human ENCODE4 cell types using Segway reveals disease driversSemantic proximity Read