Article
A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types.
Genome biology - 28 Aug 2019
Libbrecht Maxwell W, Rodriguez Oscar L, Weng Zhiping, Bilmes Jeffrey A, Hoffman Michael M, Noble William Stafford
Abstract excerpt
Semi-automated genome annotation methods such as Segway take as input a set of genome-wide measurements such as of histone modification or DNA accessibility and output an annotation of genomic activity in the target cell type. Here we present annotations of 164 human cell types using 1615 data sets. To produce these annotations, we automated the label interpretation step to produce a fully automated annotation...
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