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Article

Deficient muscle regeneration potential in sarcopenic COPD patients: Role of satellite cells.

Journal of cellular physiology - 1 Apr 2021

Sancho-Muñoz Antonio, Guitart Maria, Rodríguez Diego A, Gea Joaquim, Martínez-Llorens Juana, Barreiro Esther

Abstract excerpt

Sarcopenia is a major comorbidity in chronic obstructive pulmonary (COPD). Whether deficient muscle repair mechanisms and regeneration exist in the vastus lateralis (VL) of sarcopenic COPD remains debatable. In the VL of control subjects and severe COPD patients with/without sarcopenia, satellite cells (SCs) were identified (immunofluorescence, specific antibodies, anti-Pax-7, and anti-Myf-5): activated...

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Identifiers

PMID: 32989805
DOI: 10.1002/jcp.30073

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