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Article

Transcriptional regulation of autophagy in skeletal muscle stem cells

1 Feb 2025

Abstract excerpt

Muscle stem cells (MuSCs) are essential for the regenerative capabilities of skeletal muscles. MuSCs are maintained in a quiescent state, but, when activated, can undergo proliferation and differentiation into myocytes, which fuse and mature to generate muscle fibers. The maintenance of MuSC quiescence and MuSC activation are processes that are tightly regulated by autophagy, a conserved degradation system that...

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PMID: 39925192
DOI: 10.1242/dmm.052007

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