Article

The human acetylcholinesterase c-terminal T30 peptide activates neural growth through an alpha 7 nicotinic acetylcholine receptor mTOR pathway

2023-04-20

Abstract excerpt

Acetylcholinesterase (AChE) is a highly conserved enzyme responsible for the regulation of acetylcholine signaling within the brain and periphery. AChE has also been shown to participate in non-enzymatic activity and contribute to cellular development and aging. In particular, enzymatic cleavage of the carboxy terminal region of the synaptic AChE isoform, AChE-T, is shown to generate a bioactive T30 peptide that b...

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Literature Corpus work: f9eb5caa-95ea-5a67-9ad2-dd9be8a2702a
DOI: 10.21203/rs.3.rs-2791323/v1

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