Article

Innovative quantitative PCR assays for the assessment of HIV-associated cryptococcal meningoencephalitis in Sub-Saharan Africa

2023-08-24

Abstract excerpt

<h4>Background</h4> Cryptococcal meningitis (CM) accounts for about 10-20% of AIDS-defining illnesses with a 10-week mortality rate of 25-50%. Fungal load assessed by colony-forming unit (CFU) counts is used as a prognostic marker and to monitor response to treatment in research studies. PCR-based assessment of fungal load could be more rapid and less labor-intensive. <h4>Methods</h4> We developed and validated sp...

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Literature Corpus work: f9c4cf27-9540-5c00-b4bb-8ff407ce518e
DOI: 10.1101/2023.08.24.23294467

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