Article
Clinical epidemiology and high genetic diversity amongst Cryptococcus spp. isolates infecting people living with HIV in Kinshasa, Democratic Republic of Congo.
PloS one - 1 Jan 2022
Bive Bive Zono, Sacheli Rosalie, Situakibanza Nani-Tuma Hippolyte, Kabututu Zakayi Pius, Ka Alex, Mbula Mambimbi Marcel, Muendele Gaultier, Boreux Raphael, Landu Nicole, Nzanzu Mudogo Celestin, M'Buze Pierre-Robert, Moutschen Michel, Meyer Wieland, Mvumbi Lelo Georges, Hayette Marie-Pierre
Abstract excerpt
Neuromeningeal cryptococcosis (NMC) is a life-threatening opportunistic infection in advanced HIV disease patients (AHDP). It is caused by Cryptococcus spp. complexes and mainly occurs in sub-Saharan Africa. In this study, we performed molecular characterization and antifungal susceptibility prof...
Topics
- Antifungal Agents
- Basidiomycota
- Cryptococcosis
- Cryptococcus neoformans
- Democratic Republic of the Congo
- Genetic Variation
- Genotype
- HIV Infections
- Humans
- Multilocus Sequence Typing
- Mycological Typing Techniques