Article

Integrative Proteogenomic Analyses Identify TOPs as Prognostic Markers and Therapeutic Targets in Sarcoma

2021-01-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Soft-tissue sarcomas (STSs) are uncommon malignant tumors with varied highly aggressive and histological presentations. They comprise approximately 1% of newly diagnosed adult malignancies each year, but the sarcoma's accurate diagnosis prediction remains a challenge. TOP1/1MT/2A/2B/3A/3B were aberrantly expressed in tumors and associated with tumor progression,...

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Literature Corpus work: f961ae64-d4e8-52fc-95a3-a537a9881f0d
DOI: 10.21203/rs.3.rs-139866/v1

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