Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular landscape and therapeutic alterations in Asian soft-tissue sarcoma patients.

Cancer medicine - 1 Nov 2022

Gan Meifu, Zhang Chen, Qiu Liqing, Wang Yue, Bao Hua, Yu Ruoying, Liu Rui, Wu Xue, Shao Yang, Hou Peifeng, Fei Zhenglei

Abstract excerpt

BACKGROUND: Soft-tissue sarcoma (STS) is a rare solid malignant tumor with numerous histologic subtypes. Current studies on targeted therapy for STS are in preclinical and early-phase trials. Genomic differences largely influence the prognosis of patients even with the same subtype. To investigate the genomic alterations (GAs) and the potential of targeted therapy in STS, we analyzed the genomic landscape, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Immunotherapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Targeted Therapy

Share to Mutation

Share to Prognosis

Share to Sarcoma

Share to Soft Tissue Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 35586877
DOI: 10.1002/cam4.4725
PMCID: PMC9636498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular landscape and therapeutic alterations in Asian soft-tissue sarcoma patients.PMID 35586877Read ↗

Targetable Alterations in Adult Patients With Soft-Tissue SarcomasSemantic proximity Read ↗

Comprehensive genomic analysis of primary bone sarcomas reveals different genetic patterns compared with soft tissue sarcomasSemantic proximity Read ↗

A clinico-genomic analysis of soft tissue sarcoma patients reveals CDKN2A deletion as a biomarker for poor prognosisSemantic proximity Read ↗

Next Generation Sequencing Reveals Pathogenic and Actionable Genetic Alterations of Soft Tissue Sarcoma in Chinese Patients: A Single Center Experience.Semantic proximity Read ↗

Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targetsSemantic proximity Read ↗

Transcriptomic-Based Classification Identifies Prognostic Subtypes and Therapeutic Strategies in Soft Tissue SarcomasSemantic proximity Read ↗

Spectrum and Clinical Impact of Secondary Genetic Alterations in Translocation-Associated Sarcomas.Semantic proximity Read ↗

Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targetsSemantic proximity Read ↗

The Landscape of Alterations from 1407 Ultra-Rare Sarcomas from the AACR GENIE Database: Clinical Implications.Semantic proximity Read ↗

Molecular profiling of soft tissue sarcomas using next-generation sequencing: a pilot study toward precision therapeutics.Semantic proximity Read ↗

[Analysis of gene mutation profile of adult soft tissue sarcomas using high-throughput sequencing technology].Semantic proximity Read ↗

The landscape of gene mutations and clinical significance of tumor mutation burden in patients with soft tissue sarcoma who underwent surgical resection and received conventional adjuvant therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.