Article

Long non-coding RNA PVT1 promotes proliferation and migration of pulmonary smooth muscle cells in pulmonary arterial hypertension through miR-140-5p/Fxr1 axis

2020-07-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Pulmonary arterial hypertension (PAH) is a devastating disease and long non-coding RNAs (lncRNAs) are essential for PAH progression. Also, lncRNA plasmacytoma variant translocation 1 (PVT1) plays important roles in cell proliferation and migration, however, the effect of PVT1 on pulmonary artery smooth muscle cells (HPASMCs) in PAH remains unknown. This study ai...

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Literature Corpus work: f8ecb875-62c2-5e2b-b3a9-18f77a326f9a
DOI: 10.21203/rs.3.rs-43614/v1

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