Article

Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes

2023-05-28

Abstract excerpt

Genome-wide DNA methylation profile, or DNA methylome, is a critical component of the overall epigenomic landscape that modulates gene activities and cell fate. Single-cell DNA methylomic studies offer unprecedented resolution for detecting and profiling cell subsets based on methylomic features. However, existing single-cell methylomic technologies are all based on use of tubes or well plates and these platforms...

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Literature Corpus work: f8e13940-d13d-5366-ac65-1168989bef05
DOI: 10.1101/2023.05.26.542421

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