Article

Robust Performance of Culture, qPCR, and Genomic Approaches for Shigella Serotyping in a Pediatric Surveillance Cohort

2026-01-06

Abstract excerpt

<h4>Background</h4> Shigella causes severe diarrheal disease, and S. flexneri and S. sonnei are the targets for multivalent vaccine development. Culture-based agglutination has been the gold standard for serotyping, but it is limited by logistics, subjectivity, and the availability of antisera for emerging serotypes. Newer methods, including a qPCR-based approach and whole-genome sequencing offer alternatives,...

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Literature Corpus work: f8dabaf9-be67-5206-acb4-11e12f0ee3eb
DOI: 10.64898/2026.01.05.26343460

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