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Pathogenomic analyses of Shigella isolates inform factors limiting shigellosis prevention and control across LMICs

31 Jan 2022

Abstract excerpt

Shigella spp. are the leading bacterial cause of severe childhood diarrhoea in low- and middle-income countries (LMICs), are increasingly antimicrobial resistant and have no widely available licenced vaccine. We performed genomic analyses of 1,246 systematically collected shigellae sampled from seven countries in sub-Saharan Africa and South Asia as part of the Global Enteric Multicenter Study (GEMS) between 2007...

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PMID: 35102306
DOI: 10.1038/s41564-021-01054-z

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