Article

From Quellung to Genomics: Comparative Evaluation of Six WGS-Based Serotyping Tools for Streptococcus pneumoniae Surveillance in High-Burden Settings

2026-06-05

Abstract excerpt

<h4>Introduction: </h4> Streptococcus pneumoniae remains one of the major causes of severe life threatening illness from child to adult population. Effective monitoring of serotype distribution is crucial for nation-wide vaccine policy especially with high disease burden countries such as India. While the traditional Quellung reaction is the gold standard for pneumococcal serotyping, its implementation is limite...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a5a72f4c-1c6d-5f96-a6dd-74cd402d4d46
DOI: 10.1099/acmi.0.001252.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

From Quellung to Genomics: Comparative Evaluation of Six WGS-Based Serotyping Tools for Streptococcus pneumoniae Surveillance in High-Burden SettingsDOI 10.1099/acmi.0.001252.v1Read

SeroBA(v2.0) and SeroBAnk: a robust genome-based serotyping scheme and comprehensive atlas of capsular diversity in Streptococcus pneumoniaeSemantic proximity Read

SeroBA(v2.0) and SeroBAnk: a robust genome-based serotyping scheme and comprehensive atlas of capsular diversity in Streptococcus pneumoniae.Semantic proximity Read

The Molecular Approaches and Challenges of Streptococcus pneumoniae Serotyping for Epidemiological Surveillance in the Vaccine EraSemantic proximity Read

PfaSTer: A ML-powered serotype caller for <i>Streptococcus pneumoniae</i> genomesSemantic proximity Read

Whole-genome sequencing, strain composition, and predicted antimicrobial resistance of Streptococcus pneumoniae causing invasive disease in England in 2017–20: a prospective national surveillance studySemantic proximity Read

Robust Performance of Culture, qPCR, and Genomic Approaches for Shigella Serotyping in a Pediatric Surveillance CohortSemantic proximity Read

PneumoKITy: A fast, flexible, specific, and sensitive tool for Streptococcus pneumoniae serotype screening and mixed serotype detection from genome sequence dataSemantic proximity Read

SeroBA: rapid high-throughput serotyping of Streptococcus pneumoniae from whole genome sequence data.Semantic proximity Read

Culture-independent identification and serotyping of <i>Streptococcus pneumoniae</i> by targeted metagenomics in pleural fluid samplesSemantic proximity Read

PfaSTer: a machine learning-powered serotype caller for Streptococcus pneumoniae genomesSemantic proximity Read

Evaluation of pneumococcal serotyping in nasopharyngeal carriage isolates by latex agglutination, whole genome sequencing (PneumoCaT) and DNA microarray in a high pneumococcal carriage prevalence population in MalawiSemantic proximity Read

Bacterial genome sequencing in clinical microbiology: a pathogen-oriented reviewSemantic proximity Read