Article

Presence and Transmission of Mitochondrial Heteroplasmic Mutations in Human Populations of European and African Ancestry

2020-10-13

Abstract excerpt

<h4>ABSTRACT</h4> We investigated the concordance of mitochondrial DNA heteroplasmic mutations (heteroplasmies) in different types of maternal pairs (n=6,745 pairs) of European (EA, n=4,718 pairs) and African (AA, n=2,027 pairs) Americans with whole genome sequences (WGSs). The average concordance rate of heteroplasmies was highest between mother-offspring pairs, followed by sibling-sibling pairs and more distant...

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Literature Corpus work: f8d03885-403d-5343-a149-e7cc8bc62f2e
DOI: 10.1101/2020.10.13.337071

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