Article

Integrated gut–liver-on-a-chip platform as an <i>in vitro</i> human model of non-alcoholic fatty liver disease

2020-06-12

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) afflicts a large percentage of the population, but no effective treatments have been established so far because of the unsuitability of in vitro assays and experimental models using animals. By co-culturing human gut and liver cell lines interconnected via microfluidics for a closed circulation loop, we created a gut–liver-on-a-chip (iGLC) platform as an in vitro human m...

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Literature Corpus work: f8b0b840-5b64-53f2-b245-ee5c38c51201
DOI: 10.1101/2020.06.10.141606

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