Article

Activation of the chemokine receptor CCR1 and preferential recruitment of Gαi suppress RSV replication: implications for developing novel RSV treatment strategies

2022-03-19

Abstract excerpt

<h4>ABSTRACT</h4> Respiratory syncytial virus (RSV) is a major pathogen that can cause acute respiratory infectious diseases of the upper and lower respiratory tract, especially in children, elderly individuals and immunocompromised people. Generally, following viral infection, respiratory epithelial cells secrete cytokines and chemokines to recruit immune cells and initiate innate and/or adaptive immune response...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f88ad12e-3c65-5667-865b-ad0fc44e2fd1
DOI: 10.1101/2022.03.18.484968

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Activation of the chemokine receptor CCR1 and preferential recruitment of Gαi suppress RSV replication: implications for developing novel RSV treatment strategiesDOI 10.1101/2022.03.18.484968Read

Respiratory Syncytial Virus Infection Induces Airway Hyperresponsiveness Through miR-34b/c-5p/CXCL10 AxisSemantic proximity Read

T cell receptor signaling pathway and cytokine-cytokine receptor interaction affect the rehabilitation process after respiratory syncytial virus infectionSemantic proximity Read

The matrix protein of respiratory syncytial virus suppresses interferon signaling via RACK1 associationSemantic proximity Read

CX3CR1 Engagement by Respiratory Syncytial Virus Leads to Induction of Nucleolin and Dysregulation of Cilia-related GenesSemantic proximity Read

The Dual Role of CCR5 in the Course of Influenza Infection: Exploring Treatment Opportunities.Semantic proximity Read

Kinetics Of Interferon-λ And Receptor Expression In Response To <i>In Vitro</i> Respiratory Viral InfectionSemantic proximity Read

Respiratory syncytial virus load-dependent ciliated cell dedifferentiation and downregulation of immune response genesSemantic proximity Read

Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial VirusSemantic proximity Read

Host-dependent clinical risk factors and inflammatory cytokine levels as predictive markers of respiratory syncytial virus bronchiolitis in infantsSemantic proximity Read

Traditional Chinese medicine andrographolide sulfonate alleviates airway inflammation by supressing TRL3-TRIF in mice post respiratory syncytial virus infectionSemantic proximity Read

Biology and clinical relevance of chemokines and chemokine receptors CXCR4 and CCR5 in human diseasesSemantic proximity Read

Respiratory syncytial virus modifies microRNAs regulating host genes that affect virus replicationSemantic proximity Read