Article

Respiratory Syncytial Virus Infection Induces Airway Hyperresponsiveness Through miR-34b/c-5p/CXCL10 Axis

2021-05-05

Abstract excerpt

<h4>Background: </h4> There is growing evidence on miRNAs with pivotal role in viral infection-induced airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). However, the related mechanism of RSV infection affecting airway inflammation and airway hyperresponsiveness (AHR) is largely unknown. <h4>Methods: </h4>： We obtained the miRNA and mRNA databases of patients with RSV infection, as we...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 741164b0-ddc3-5211-940a-46d504d2272d
DOI: 10.21203/rs.3.rs-457637/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Respiratory Syncytial Virus Infection Induces Airway Hyperresponsiveness Through miR-34b/c-5p/CXCL10 AxisDOI 10.21203/rs.3.rs-457637/v1Read

Respiratory syncytial virus infection‐induced mucus secretion by down‐regulation of miR‐34b/c‐5p expression in airway epithelial cellsSemantic proximity Read

T cell receptor signaling pathway and cytokine-cytokine receptor interaction affect the rehabilitation process after respiratory syncytial virus infectionSemantic proximity Read

IFI27 may predict and evaluate the severity of respiratory syncytial virus infection in preterm infantsSemantic proximity Read

Respiratory syncytial virus modifies microRNAs regulating host genes that affect virus replicationSemantic proximity Read

IFI27 may predict and evaluate the severity of respiratory syncytial virus infection in preterm infants.Semantic proximity Read

Activation of the chemokine receptor CCR1 and preferential recruitment of Gαi suppress RSV replication: implications for developing novel RSV treatment strategiesSemantic proximity Read

Ligand/Receptor-mediated Cell Communication Alteration Causes the Lung Inflammation Microenvironment and the Redistribution of Inter-tissue Immune Cells in COVID-19 PatientsSemantic proximity Read

Non-Coding RNA in Idiopathic Interstitial Pneumonia and Covid-19 Pulmonary FibrosisSemantic proximity Read

The Novel Regulatory Role of the lncRNA–miRNA–mRNA Axis in Chronic Inflammatory Airway DiseasesSemantic proximity Read

Exploring Inflammatory Dysregulation in Alveolar Macrophages: Implications for Novel Therapeutic Targets in Chronic Obstructive Pulmonary DiseaseSemantic proximity Read

Identification of potential key genes for SARS-CoV-2 infected human bronchial organoids based on bioinformatics analysisSemantic proximity Read

The Molecular Basis of Asthma Exacerbations Triggered by Viral Infections: The Role of Specific miRNAsSemantic proximity Read