Article

dream: Powerful differential expression analysis for repeated measures designs

2018-10-03

Abstract excerpt

<h4>ABSTRACT</h4> Large-scale transcriptome studies with multiple samples per individual are widely used to study disease biology. Yet current methods for differential expression are inadequate for cross-individual testing for these repeated measures designs. Most problematic, we observe across multiple datasets that current methods can give reproducible false positive findings that are driven by genetic regulati...

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Literature Corpus work: f8764435-a176-55fc-8cbc-897d418b97ea
DOI: 10.1101/432567

Open publication

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