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Article

Dynamics of global transcriptome in bovine matured oocytes and preimplantation embryos

1 Dec 2006

Abstract excerpt

Global activation of the embryonic genome is the most critical event in early mammalian development. After fertilization, a rich supply of maternal proteins and RNAs support development whereas a number of zygotic and embryonic genes are expressed in a stage-specific manner leading to embryonic genome activation (EGA). However, the identities of embryonic genes expressed and the mechanism(s) of EGA are poorly...

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PMID: 17142320
DOI: 10.1073/pnas.0608247103

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