Article

RNA secondary structure packages evaluated and improved by high-throughput experiments

2020-05-31

Abstract excerpt

The computer-aided study and design of RNA molecules is increasingly prevalent across a range of disciplines, yet little is known about the accuracy of commonly used structure modeling packages in tasks sensitive to ensemble properties of RNA. Here, we demonstrate that the EternaBench dataset, a set of over 20,000 synthetic RNA constructs designed in iterative cycles on the RNA design platform Eterna, provides inc...

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Literature Corpus work: f82c7fc1-fb1e-5d7d-9109-6f073fba074c
DOI: 10.1101/2020.05.29.124511

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